I want to share a link to a recent news report about Bravecto, to which I contributed. I agreed to be interviewed for this story for one reason: I continue to search for someone in the scientific community with the knowledge and facilities to help me investigate why this drug causes side effects in some animals. Before anyone jumps in saying “there are no side effects with Bravecto,” please keep in mind that even the manufacturer lists side effects on the product insert. I believe if we can understand the mechanism, we can make the use of the drug safer. At present, with thousands of doses administered to dogs (and now cats) around the world every month, doesn’t it make sense to improve our understanding of how the drug impacts the dog or cat’s body? Let us keep in mind that this class of drugs (isoxazolines) has been in use in dogs around the world for just over 2 years.
Two important points to keep in mind if you watch the video:
I. The manufacturer states the incidence of reported side effects is very low. However, this figure depends entirely on how many people actually file a report.
Underreporting occurs with most adverse event reporting systems. (FDA Center for Veterinary Medicine)
II. Many people are clamoring for proof. “Show me proof that Bravecto killed a dog.” Well, we can’t because there is no pre- or post-mortem test to do so. I have read at least a dozen necropsy reports in the past year. I’ve reached out to some of the pathologists who wrote the reports. I’ve communicated with a veterinary pharmacologist and a veterinary toxicologist. Not one of these professionals has yet been able to answer questions about “proof.”
I know there are many strong feelings about all of this, on both sides of the aisle. You are welcome to comment but I would ask that everyone keep it civil. If anyone has a background in mammalian pharmacology/toxicology and a laboratory and wants to work with me, please contact me!